Cardiac allograft vasculopathy: diagnosis, therapy, and prognosis
نویسندگان
چکیده
منابع مشابه
Cardiac allograft vasculopathy: diagnosis, therapy, and prognosis
Development of cardiac allograft vasculopathy represents the major determinant of long-term survival in patients after heart transplantation. Due to graft denervation, these patients seldom present with classic symptoms of angina pectoris, and the first clinical presentations are progressive heart failure or sudden cardiac death. Although coronary angiography remains the routine technique for c...
متن کامل[Diagnosis, prevention and treatment of cardiac allograft vasculopathy].
The major limitation of long-term survival after cardiac transplantation is allograft vasculopathy, which consists of concentric and diffuse intimal hyperplasia. The disease still has a significant incidence, estimated at 30% five years after cardiac transplantation. It is a clinically silent disease and so diagnosis is a challenge. Coronary angiography supplemented by intravascular ultrasound ...
متن کاملDiagnosis of cardiac allograft vasculopathy: Challenges and opportunities.
Cardiac allograft vasculopathy (CAV) is one of the most common long-term complications in patients following heart transplantation. Because of its irreversible nature, early detection is essential to impact progression. Thus, imaging techniques play a crucial role in the diagnosis and subsequent treatment. Major advancements in imaging and analysis are required to overcome the limitations of cu...
متن کاملCardiac allograft vasculopathy: recent developments.
Cardiac allograft vasculopathy (CAV) continues to limit the long-term success of cardiac transplantation. Recent insights have underscored the fact that innate and adaptive immune responses are involved in the pathogenesis of CAV. Vascular lesions are the result of cumulative endothelial injuries induced both by alloimmune responses and by nonspecific insults (including ischemia-reperfusion inj...
متن کاملCardiac allograft vasculopathy: a review.
Cardiac allograft vasculopathy (CAV) is a major factor limiting long-term survival after cardiac transplantation. CAV is an accelerated form of coronary artery disease (CAD) that is characterized by concentric fibrous intimal hyperplasia along the length of coronary vessels. Both immunologic and nonimmunologic risk factors contribute to the development of CAV by causing endothelial dysfunction ...
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ژورنال
عنوان ژورنال: Croatian Medical Journal
سال: 2014
ISSN: 0353-9504,1332-8166
DOI: 10.3325/cmj.2014.55.562